Cristina Yang has little sympathy for Constance Ferguson (special guest star Rosanna Arquette), a prison inmate who jeopardizes her health just to get out of solitary confinement. Meanwhile the interns all keep careful watch on the family of premature quintuplets with a variety of serious health challenges, Izzie's anger at Alex reaches boiling point, and Dr. Addison Shepherd decides to teach Izzie a very painful lesson. false 2017-10-04 02:34:44 Chandra Wilson Daniel Minahan Ellen Pompeo Isaiah Washington James Pickens Jr. Justin Chambers Kate Walsh Katherine Heigl Patrick Dempsey Sandra Oh T.R. Knight 8.5 2005 tt0592916 306114 42 Drama Romance https://www.thetvdb.com/banners/episodes/73762/306114.jpg Curtis Armstrong GuestStar https://image.tmdb.org/t/p/original/vXR54kdnRTJn25tuhRevA9jSbrj.jpg Margaret Welsh GuestStar Pat Healy GuestStar https://image.tmdb.org/t/p/original/nZOPsq538w5ekft8PsOjcx5UN6f.jpg Rosanna Arquette GuestStar https://image.tmdb.org/t/p/original/lmNtgobpREc2ELRqJwA5nH8oAGF.jpg Sarah Utterback GuestStar Timothy Bottoms GuestStar https://image.tmdb.org/t/p/original/qF99X2tCETDjqV9msKsp7CA6usC.jpg 11 2 2005-12-04